Gements The contributions from the Korean Society of Hypertension and Hanmi Pharmaceuticals are gratefully acknowledged. Funding This analyze was supported by a analysis grant from Hanmi Pharmaceutical Co., Ltd. (HM-IIT-AMST-003). Availability of knowledge and supplies Not applicable. Authors’ contributions OGC wrote the manuscript. CWJ, YHJ, CEJ, SKC, CSC, YBS, PCG, HSJ, KYK, HTJ, CDJ, HMS, HJW, KYJ, AY, CMC, KSG, SJ, PS, and SIS participated from the style and design in the research. KCJ and LHY developed the analyze, wrote the manuscript, and gave remaining approval in the variation to be posted. All authors go through and authorised the ultimate manuscript. Ethics acceptance and consent to take part This trial is going to be carried out in accordance using the declaration of Helsinki. All investigators might be necessary to receive approval through the institutional evaluation boards (IRB) from each individual taking part center. All clients will signal a created consent variety authorized from the IRB. The examine is likewise in accordance to your Korean very good clinical apply (KGCP) plus the global conference on harmonizationgood clinical practice (ICH-GCP). (Clinicaltrials.gov Identifier: NCT02294539). Consent for publication Although the manuscript won’t involve any clinical info, consent will probably be obtained for that info for being printed with the time of recruitment into your study. Competing pursuits The authors declare which they don’t have any competing passions.Publisher’s NoteSpringer Mother nature remains neutral with regards to jurisdictional promises in released maps and institutional affiliations. Author facts 1 Division of Cardiology, Division of Inner Medication, Seoul National College Medical center, Seoul, Korea. 2Division of Cardiovascular disease, Division of Inner Medication, Gachon University Gil Hospital, Professional medical Middle, Incheon, Korea. 3Department of Cardiology, Cardiovascular Centre, Seoul St. Mary’s Healthcare facility, Seoul, Korea. 4Division of Cardiology, St. Paul’s Clinic, Seoul, Korea. 5Division of Cardiology, Department of medicine, Kangbuk Samsung Medical center, Seoul, Korea. 6Division of Cardiology, Section of Internal PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/6146108 Drugs, Kyungpook Countrywide University Healthcare facility, Daegu, Korea. 7Division of Cardiology, Department of Inside Medicine, Yonsei University Wonju Clinic, Wonju, Korea. 8Department of Cardiology, Korea University Guro Medical center, Seoul, Korea. 9Department of Cardiology,Oh et al. Medical Hypertension (2017) 23:Web site 6 ofCardiovascular Middle, Korea University Anam Clinic, Seoul, Korea. 10 Division of Cardiology, Section of Interior Medication, Dongguk University Ilsan Hospital, Goyang, Korea. 11Division of Cardiology, Division of Inner Medicine, Pusan National College Healthcare facility, Busan, Korea. 12 Cardiovascular Centre, Division of Cardiology, Seoul National College Bundang Medical center, Seongnam, Korea. 13Division of Cardiology, Division of Inside Medication, Soonchunhyang Seoul Hospital, Seoul, Korea. 14Division of Cardiology, PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/16382199 Section of Inside Medication, Severance Cardiovascular Hospital, Seoul, Korea. 15Division of Cardiology, Division of Inside Drugs, Yeungnam University Medical center, Busan, Korea. 16Division of Cardiology, Division of Inner SKF 38393 hydrobromide Medicine, Chonnam Countrywide University Medical center, Gwangju, Korea. 17Division of Cardiology, Office of Internal Medicine, Chungbuk Nationwide College Medical center, Cheongju, Korea. 18Division of Cardiology, Section of Internal Drugs, Hanyang College Guri Healthcare facility, Guri, Korea. 19Division of Cardiology, Office of In.

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